The Nikkei 225 Index rose 0.07% to close at 48,659 while the Topix Index lost 0.21% to 3,291 on Tuesday, struggling for clear direction as markets reopened after a holiday-extended weekend.
Japanese shares initially followed tech-led gains on Wall Street overnight amid renewed optimism around artificial intelligence and rising hopes for a Federal Reserve interest rate cut in December.
Technology stocks showed mixed performances locally, with gains from Advantest (4.2%) and Tokyo Electron (3.1%), while sharp losses were record in SoftBank Group (-10%)a nd Disco Corp (-2.7%). Meanwhile, Eisai which co-developed Alzheimer's treatment Lequembi surged 7.4% after Novo Nordisk said clinical trials of its semaglutide drug failed to slow the progression of the illness.
Source: Trading Economi
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