Wall Street's indexes closed at record highs on Wednesday, buoyed by strong sector performance and optimism that the US government shutdown will be brief. Investors shrugged off the first day of the shutdown and weaker-than-expected private payrolls data, with the S&P 500 gaining 0.3%, the Nasdaq 100 rising 0.5%, and the Dow adding 43 points. Health-care stocks led the advance, driven by sharp gains in Regeneron (+6.7%), Moderna (+6.8%), Eli Lilly (+8.2%), and AbbVie (+5.5%), while optimism over Pfizer's (+2.2%) deal with the White House on Medicaid drug pricing provided additional...
Europe's STOXX 600 closed at a record high on Wednesday, with healthcare stocks leading the way after a U.S.-Pfizer deal reduced uncertainty in the sector, while investors digested the beginning of a U.S. government shutdown. The pan-European STOXX 600 surged 1.2% to log its biggest one-day percentage gain since July 23. Most regional bourses were also trading higher, with London's FTSE 100 at a record high. Healthcare stocks jumped 5.4%, marking their biggest one-day performance since November 2008. On Tuesday, Pfizer agreed to lower prescription drug prices in the U.S. Medicaid programme...
European shares were flat on Wednesday, with gains in heavyweight healthcare stocks offsetting the decline in the broader market, as investors fretted over a potential delay in the closely-watched U.S. jobs data. The pan-European STOXX 600 held steady at 557.9 points by 0711 GMT, after posting its third successive monthly gain in September. Local bourses were mixed. Germany's DAX was down 0.5%, while the UK's FTSE 100 climbed 0.2% to an all-time high. Healthcare stocks jumped 2.7% after Pfizer and U.S. President Donald Trump on Tuesday said they had cut a deal in which the drugmaker...
The Nikkei 225 fell 0.85% to 44,551 while the broader Topix dropped 1.37% to 3,095 on Wednesday, extending this week's declines as investors digested mixed economic signals. Business sentiment among large manufacturers improved in Q3 to its highest level since Q4 2024, though US tariff pressures continued to cloud the outlook. Meanwhile, weak readings in retail sales and industrial production highlighted persistent economic headwinds. Sentiment was further dampened by the US government shutdown after lawmakers failed to agree on a temporary funding deal, raising concerns over its duration...
Asia-Pacific markets opened mixed Wednesday, following gains on Wall Street ahead of a potential U.S. government shutdown as lawmakers continue to wrangle over details of a second temporary spending bill. Investors in Asia will look toward the Reserve Bank of India's rate decision late Wednesday. Japan's Nikkei 225 sunk 0.2% at its open, while the broad based Topix was down 0.85%. In South Korea, the blue-chip Kospi was up 0.94%, and the small-cap Kosdaq gained 0.84%. Australia's S&P/ASX 200 slipped 0.32% in early trade. Markets on mainland China and Hong Kong were closed for a...